K72
Conditions
Interventions
Group 1: Absorbertherapy
Sponsors
Uniklinik RWTH Aachen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: ACLF with intensive care treatment and ongoing renal replacement therapy through an indwelling catheter, and indication for absorbertherapy
Exclusion criteria
Exclusion criteria: Pregnancy Acute Liver Failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic stabilization, as indicated by reduction of vasopressor dosage and MAP (mean arterial pressure) in patients receiving absorption therapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| - 30-day-and 60-day-mortality - Length of stay (LOS) on ICU - Indicators for stabilization of inflammatory conditions, such as white blood cell count, differential analyses of neutrophils and monocytes - Serum CRP, PCT, IL6, IL10 and TNFa - Serum bile acid concentrations - Serum bilirubin concentrations - Liver organ function, as indicated by INR and coagulation factor V | — |
Countries
Germany
Contacts
Public ContactAlexander Koch
Uniklinik RWTH Aachen
Outcome results
None listed