R91
Conditions
Interventions
Group 1: If an IPN with a lesion size of =8 to 30 mm is detected during non-oncologically indicated CT examinations of the thorax (e.g. cardiac issues or lung diseases), FDG-PET/CT is performed in acc
Sponsors
DKFZ-Hector Krebsinstitut an der Universitätsmedizin Mannheim
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: -Patients with at least 1 detected lung lesion (5-30mm) in the CT thorax -No oncological disease in the last 5 years
Exclusion criteria
Exclusion criteria: -Lack of ability to be informed -Legal care -Lack of consent to the study -Pregnancy (no inclusion of pregnant women)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rate and discrimination of IPN according to their malignancy risk | — |
Secondary
| Measure | Time frame |
|---|---|
| - Evaluation of the sensitivity and image quality of LAFOV FDG-PET/CT and photoncounting CT in the detection of IPN - Biopsy of IPN using preinterventional diagnostics on photoncounting CT vs. LAFOV FDG-PET/CT - Prediction of the clinical course (e.g. progression-free survival, overall survival) based on image parameters in photoncounting CT vs. LAFOV FDG-PET/CT - Correlation between FDG enrichment in LAFOV PET/CT and other clinical parameters (histological clinical parameters (histological tumour stage, laboratory parameters) | — |
Countries
Germany
Contacts
Public ContactFreba Grawe
DKFZ-Hector Krebsinstitut an der Universitätsmedizin Mannheim
Outcome results
None listed