Open- label placebo effects in adolescents: An experimental investigation of placebo effects on sadness

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00033529

Enrollment

Registered

2024-02-23

Start date

2023-02-17

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Experimentally induced subjective sadness

Interventions

Group 1: Single intake of an active placebo nasal spray Group 2: Passive control group (no placebo intake)

Eligibility

Sex/Gender

All

Age

12 Years to 17 Years

Inclusion criteria

Inclusion criteria: German speaking, no current diagnosis of a mental disorder known (self-report of parents)

Exclusion criteria

Exclusion criteria: Reported current mental disorder, allergies against ingredients of the placebo, acute operation or injury to the nose, asthma

Design outcomes

Primary

Measure	Time frame
Subjective sadness (assessed with the PANAS-C: Positive and Negative Affect Schedule, translated into German), before and after each mood induction procedure	—

Secondary

Measure	Time frame
Change in peripheral physiological correlates during mood induction phases	—

Countries

Germany

Contacts

Public ContactAlannah Hahn

Justus-Liebig-Universität Giessen

Alannah.Hahn-2@psychol.uni-giessen.de+496419926097

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026