Blepharitis
Conditions
Interventions
Group 1: Treatment with BlephEx® according to the manufacturer's treatment recommendation.
Group 2: Sham treatment
Sponsors
Klinik für Augenheilkunde, Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: symptomatic blepharitis (at least Grade 2 according to the Efron grading scale), age older than 18 years, decimal visual acuity >0.5, blepharitis refractory to eyelid margin care and the use of lubricating drops for at least 4 weeks
Exclusion criteria
Exclusion criteria: routine (daily) contact lens wear, other eyelid or ocular surface diseases, previous ocular surgery, previous treatment with cyclosporin A or steroids, pregnancy, autoimmune diseases (e.g. Sjögren's syndrome, endocrine orbitopathy) or other immunological diseases and acute infections. Further exclusion criteria were the presence of trachoma, atopic dermatitis, diabetes mellitus, severe systemic diseases, graft-versus-host disease or the use of antibiotics in the last 4 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survey using a standardized questionnaire on dry eye (OSDI) | — |
Secondary
| Measure | Time frame |
|---|---|
| Tear film break-up time; Efron Grading Scale: grading of blepharitis at the eyelid margin | — |
Countries
Germany
Contacts
Public ContactPhilip Maier
Klinik für Augenheilkunde, Universitätsklinikum Freiburg
Outcome results
None listed