Q25.1
Conditions
Interventions
Group 1: At the time of presentation, the intima-media thickness (IMT) and roughness (IMR) in the carotid, brachial and femoral arteries will be measured once using high-resolution ultrasound and vasc
Sponsors
LMU Klinikum Großhadern
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: Normal population: healthy male and female subjects between 18-30 years of age without previous cardiovascular disease, normal weight, i.e. BMI <25 kg/m2 Subjects with specially operated aortic coarctation: male and female subjects between 18-30 years of age who had aortic coarctation surgery in the Department of Pediatric Cardiology and Pediatric Intensive Care Medicine at Ludwig-Maximilians-Universität, or who are undergoing follow-up care there, subclavian-flap technique only Subjects with aortic coarctation surgery: male and female subjects between 18-30 years of age who had aortic coarctation surgery at the Department of Pediatric Cardiology and Pediatric Intensive Care at Ludwig-Maximilians-University, or who are undergoing follow-up care there, no subclavian flap technique
Exclusion criteria
Exclusion criteria: Other serious diseases of the cardiovascular system (e.g. heart failure, cardiac arrhythmia, arteriosclerosis, PAD), metabolic diseases (e.g. lipid metabolism disorder requiring therapy, hypercholesterolemia, diabetes mellitus type 1 and 2), sudden cardiac death in the family
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intima-media thickness (IMT), intima-media roughness (IMR) and vessel stiffness measured by high-resolution ultrasound at the time of presentation | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular risk: heart rate, blood pressure, height, weight, waist circumference, BMI, body fat, lean body mass, LDL, HDL, cholesterol, triglycerides, small blood count, fitness test. Medical history: physical fitness, weekly activity, weight. | — |
Countries
Germany
Contacts
Public ContactNikolaus Haas
LMU Klinikum Großhadern
Outcome results
None listed