K70 K71 K72 K73 K74 K75 K76 K77 C22
Conditions
Interventions
Group 1: If machine perfusion is planned (dual hypothermic oxygenated machine perfusion/DHOPE), the donor organ is first prepared “backtable”. A tissue sample - a 4 cm long cylinder - is taken from a
Sponsors
Universitätsklinik für Allgemein-, Viszeral-, Gefäß- und Transplantationschirurgie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Terminal liver disease as an indication for transplantation (except HU) - Tumor diseases as an indication for transplantation
Exclusion criteria
Exclusion criteria: Chronic renal failure (GFR < 45 ml/min) - Iodine allergy - Hyperthyroidism - Known allergy to ICG
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study endpoint is to predict liver function via ICG clearance after machine perfusion via an extracorporeal function test of the liver using a procedure already established as a preoperative liver function test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Further study endpoints, such as postoperative complications (severity > 3 according to Clavien-Dindo classification), 30-day mortality, acute rejection, re-transplantation, EAD, primary non-function (PNF) should be recorded and with the examined parameters from the samples taken can be correlated. | — |
Countries
Germany
Contacts
Public ContactAntonia Bollensdorf
Universitätsklinik für Allgemein-, Viszeral-, Gefäß- und Transplantationschirurgie
Outcome results
None listed