Impact of mild hypo- and hyperventilation on cerebral oxygen supply during general anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00033414

Enrollment

Registered

2024-01-16

Start date

2020-02-26

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral oxygen saturation

Interventions

Group 1: Patients with general anesthesia (Age 60 years)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. consent of the patient 2. surgery under general anesthesia

Exclusion criteria

Exclusion criteria: 1. age < 18 years 2. refusal of the patient 3. Patients after apoplex 4. hemodynamically relevant carotid stenosis 5. post neurosurgical intervention 6. normal pressure hydrocephalus 7. arterial hypertension 8. COPD

Design outcomes

Primary

Measure	Time frame
NIRS value (near infrared spectroscopy) in comparison between end-tidal CO2 at the lower standard limit and the upper standard limit.	—

Secondary

Measure	Time frame
Difference in NIRS value between young and older patients	—

Countries

Germany

Contacts

Public ContactKlaus Hofmann-Kiefer

LMU Klinikum

klaus.hofmann-kiefer@med.uni-muenchen.de089 4400 52695

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026