Availability of anthocyanins from carrot drinks in overweight and obese subjects and their effect on immune-associated vascular parameters

Availability of anthocyanins from carrot drinks in overweight and obese subjects and their effect on immune-associated vascular parameters - ViolED-Studie - Violet-blue Anthocyanins and their Effect on activated Monocytes to Endothelial Dysfunctional Cells

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00033405

Enrollment

Registered

2024-01-12

Start date

2026-01-01

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E66.9

Interventions

Group 1: Verum group: intake of 60 mL carrot shot (2000 mg/L anthocyanins) per day for 28 days. Group 2: Placebo group: intake of 60 mL of placebo shot (0 mg/L anthocyanins) per day for 28 days

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: healty with BMI = 27-29,9 kg/m²

Exclusion criteria

Exclusion criteria: Vegetarians, vegans, colds, allergies, taking medication, taking supplements of any kind

Design outcomes

Primary

Measure	Time frame
Distribution of CD14/CD16 monocyte subpopulations (day 0 vs. day 28)	—

Secondary

Measure	Time frame
Activation of the NLRP3 inflammasome (ASC, NLRP3 and IL-1ß expression, caspase-1 activity, IL-1ß and IL-18 concentration in cell culture supernatant)	—

Countries

Germany

Contacts

Public ContactSabine Kuntz

Justus Liebig Universität Giessen, Institut für Ernährungswissenschaft

sabine.kuntz@ernaehrung.uni-giessen.de06419939082

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026