2) Long-term ventilated patients with respiratory failure (ARDS)
Conditions
Interventions
Group 1: Two formally distinct groups of mechanically ventilated intensive care patients are eligible for study inclusion:
I. Patients who, on our intensive care unit (UMG, Station 0119), are long-ter
Sponsors
Universitätsmedizin Göttingen, Klinik für Anästheisologie & Klinik für Neurologie
Eligibility
Sex/Gender
All
Age
18 Years to 91 Years
Inclusion criteria
Inclusion criteria: Female and male mechanically ventilated intensive care patients
Exclusion criteria
Exclusion criteria: Age 91 years - Refusal to participate in the study - No existing consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The goal of this observational study is to establish a correlation between the consciousness state/sedation depth (in terms of an absolute numerical EEG oscillation frequency value or processed EEG) of mechanically ventilated intensive care patients during the weaning phase from the ventilator and the quality and quantity of respiratory effort. The below-listed data and measurement methods are recorded during the course of ventilation and/or sedation in the intensive care unit. Measurement instruments/parameters for sedation: -NarcotrendR, Massimo Root® with SedLine®, or BIS monitoring measured numerical absolute EEG value of EEG oscillation frequency (corresponding to sedation depth/consciousness state) -Sedative medications -Other Monitoring Parameters Measurement instruments/parameters for the ventilator (SERVO-U®): -Respiratory rate (RR) -Ratio of Tidal Volume (tV)/Ideal Tidal Volume (itV) -Additional ventilation parameters (minute volume, FiO2, PIP, PEEP, PS (Delta), airway occlusion pressure (P0.1), NAVA level, etc.) -Other parameters from the Ventilator -Breathing pattern (clinical assessment) Specific data Cumulative sedation dose, sedation depth, regional oxygen saturation, arterial oxygen concentrations, arterial carbon dioxide concentrations, arterial pH values, blood glucose levels, cumulative dose of glucose administration, JH-ACE, IQCODE, CAM-ICU, RASS (Richmond Agitation-Sedation Scale), possibly additional routinely collected parameters from arterial blood gas analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic data, age at study enrollment, gender, admission diagnosis, primary diagnoses, pre-existing conditions, comorbidities, SAPS II at admission, SOFA score, in the case of ARDS severity, duration of invasive ventilation, length of stay in the ICU, hospital length of stay, hospital mortality, ICU mortality, possibly additional routinely collected parameters. | — |
Countries
Germany
Contacts
Public ContactIvan Chakalov
Universitätsmedizin Göttingen, Klinik für Anästheisologie & Klinik für Neurologie
Outcome results
None listed