Sonographic mapping of diaphragmatic contractility in diaphragmatic dysfunction of different etiologies

Sonographic mapping of diaphragmatic contractility in diaphragmatic dysfunction of different etiologies - DiaMap I

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00033342

Enrollment

Registered

2024-01-03

Start date

2024-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J98.6

Interventions

Group 1: In the case of unilateral diaphragmatic paresis, in addition to the standard diaphragm sonography in the anterior axillary line, further sounding points are examined in the medioclavicular li

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Age = 18 years - Diagnosis of unilateral diaphragmatic dysfunction - Informed and signed consent

Exclusion criteria

Exclusion criteria: - Bilateral diaphragmatic paresis - Persons who are in a dependent or employment relationship with the examiner - Placement in an institution due to a court or official order - Incapacitated patients - Pregnancy and breastfeeding

Design outcomes

Primary

Measure	Time frame
Mapping of diaphragmatic contractility by sonographic measurement of the "thickening fraction" (TF%) in the apposition zone of the diaphragm during palpation - medioclavicular - in the anterior, middle and posterior axillary line - and medioscapular with reference to the underlying etiology of the diaphragmatic dysfunction.	—

Secondary

Measure	Time frame
Comparison between the affected side of the diaphragm and the healthy side of the diaphragm - Sonographic mapping of the diaphragmatic thickness in the above-mentioned positions with reference to the underlying etiology and the duration of the diaphragmatic dysfunction - Magnetic resonance imaging mapping of denervation edema in the muscular parts of the diaphragm as a correlate of an axonal lesion of parts of the respective phrenic nerve in a subgroup of subjects with onset of symptoms <= 3 months earlier	—

Measure

Time frame

Comparison between the affected side of the diaphragm and the healthy side of the diaphragm - Sonographic mapping of the diaphragmatic thickness in the above-mentioned positions with reference to the underlying etiology and the duration of the diaphragmatic dysfunction - Magnetic resonance imaging mapping of denervation edema in the muscular parts of the diaphragm as a correlate of an axonal lesion of parts of the respective phrenic nerve in a subgroup of subjects with onset of symptoms <= 3 months earlier

—

Countries

Germany

Contacts

Public ContactMaximilian Zimmermann

Kliniken der Stadt Köln

zimmermannma@kliniken-koeln.de0221890713468

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026