F06.7
Conditions
Interventions
Group 1: One time interview with 45 min. duration with n= 10 patients with mild cognitive impairment
Group 2: One time interview with 45 min. duration with n= 10 patients with subjective cognitive dec
Sponsors
Klinik für Psychiatrie und Psychotherapie, Uniklinik Köln
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: SCD patients: - Clinical criteria for the diagnosis of SCD (according to the criteria of Jessen et al. 2014): - Subjective and persistent (non-acute) deterioration in cognitive performance compared to the original baseline level unrelated to an acute event - Neuropsychological test battery used for MCI or prodromal AD shows findings within the age-, gender- and education-adjusted norm group - Written informed consent of the patient - Age = 60 years MCI patients: - Memory performance 1.5 standard deviation below the age-, gender- and education-adjusted norm group - Impairment in one or more cognitive domains - Self-reported or external history of cognitive impairment - Activities of daily living (ATLs) obtained - Biomarker evidence of Alzheimer's disease (amyloid and tau pathology) - Written informed consent of the patient - Age = 60 years
Exclusion criteria
Exclusion criteria: SCD patients: - insufficient knowledge of the German language - illiteracy - MCI, prodromal AD or dementia -Impairments can be explained by a psychiatric* or neurological illness (excluding AD), somatic illness, medication or substance abuse - Moderate to severe depressive symptoms or anxiety symptoms * Mild subsyndromal depressive symptoms or anxiety symptoms do not count as exclusion MCI patients: - Insufficient knowledge of the German language - illiteracy - dementia - Evidence of a non-AD neurodegenerative disease such as: Parkinson's disease, Lewy body dementia, frontotemporal lobar degeneration, very rapid cognitive deterioration within a few weeks or months (classically indicative of a prion disease, neoplasia or metabolic disorder) - Brain tumor - Evidence of cerebrovascular disease in structural imaging, which serves as an indication of a vascular genesis of the cognitive impairment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dementia risk perception by means of interviews and body mapping | — |
Secondary
| Measure | Time frame |
|---|---|
| Affective wellbeing and psychosocial needs by means of interviews and body mapping | — |
Countries
Germany
Contacts
Public ContactAyda Rostamzadeh
Klinik für Psychiatrie und Psychotherapie, Uniklinik Köln
Outcome results
None listed