Hereditary Myopathies idiopathic inflammatory myopathies
Conditions
Interventions
Group 1: Repeated examination of the skeletal muscles using MSOT for longitudinal observation and correlation with disease progression, Inclusion of patients with myopathies and non-myopathic controls
Sponsors
Universitätsmedizin Göttingen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Confirmed diagnosis of a myopathy evaluated in this study - able to give consent
Exclusion criteria
Exclusion criteria: - Unclear neuromuscular disorder or symptoms, NMD not evaluated in this study - unable to give consent - pregnancy - tattoos of the skin in the examinated area - severe peripheral arterial disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Optoacoustic absorption spectrum of skeletal muscle in different myopathies | — |
Secondary
| Measure | Time frame |
|---|---|
| MSOT: quantitative lipide, collagen, haemo-/myoglobine, glycogene signal, muscle oxygenation RUCT (Hybrid reflected ultrasound computed tomography): Heckmatt scale, echogenity, grey value Clinical parameters: muscle strength, grip strength, 6 minute walking test, time to get up and go test Disease specific patient reported scales Vital capacity | — |
Countries
Germany
Contacts
Public ContactJana Zschüntzsch
Universitätsmedizin Göttingen, Klinik für Neurologie
Outcome results
None listed