“Effects of a training recommendation for post-COVID-19 syndrome (pilot study)”

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00033162

Enrollment

Registered

2023-12-01

Start date

2024-02-12

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

U09.9

Interventions

Group 1: Intervention group: The intervention group is recommended to slowly increase first the frequency (from 3 to 5 per week within the first four weeks of training) and then the duration (from 15

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. SARS-CoV-2 infection (positive PCR or rapid antigen test), evidence of SARS-CoV-2 infection 12 weeks ago 2. Indication of a subjective reduction in performance/restrictions in everyday life (FAS score 22) 3. Echocardiography examination with LV function 50%; Time of investigation after the complaint began 4. Suitable for sports intervention according to the S1 guideline 5. Signed informed consent

Exclusion criteria

Exclusion criteria: 1. Presence of an acute other internal or neurological/psychiatric illness that explains the symptoms 2. Inability or medical unsuitability to take part in a sports intervention: SpO2 under exercise 90% or evidence of warning signs as part of the basic diagnostics 3. Presence of chronic fatigue syndrome (CFS) according to the diagnostic criteria of the Canadian Consensus criteria 4. Pacemaker 5. Atrial fibrillation 6. Pregnancy

Design outcomes

Primary

Measure	Time frame
Improving functional status: EQ-5D-5L (SCORE)	—

Secondary

Measure	Time frame
1. Reducing the occurrence of PEM through specific training advice: DePaul Symptom Questionnaire - PEM (DSQ-PEM) 2. Improvement of cardiorespiratory performance: spiroergometric parameters VO2 peak, W max, O2 uptake at VT1; hemodynamic parameters and change in autonomic balance 3. Change in vascular stiffness: pulse wave velocity, aortic augmentation index, return time of aortic pulse wave 4. Analysis regarding physical activity completed: metabolic equivalents (MET) hours per day from fitness tracker plus activity diaries 5. exploratory data analysis regarding cognitive or psychological / psychosomatic impairments: evaluated, standardized questionnaires	—

Measure

Time frame

1. Reducing the occurrence of PEM through specific training advice: DePaul Symptom Questionnaire - PEM (DSQ-PEM) 2. Improvement of cardiorespiratory performance: spiroergometric parameters VO2 peak, W max, O2 uptake at VT1; hemodynamic parameters and change in autonomic balance 3. Change in vascular stiffness: pulse wave velocity, aortic augmentation index, return time of aortic pulse wave 4. Analysis regarding physical activity completed: metabolic equivalents (MET) hours per day from fitness tracker plus activity diaries 5. exploratory data analysis regarding cognitive or psychological / psychosomatic impairments: evaluated, standardized questionnaires

—

Countries

Germany

Contacts

Public ContactDörte Ahrens

Universitätsklinik für Kardiologie und Angiologie

doerte.ahrens@med.ovgu.de+49-0391-67-13236

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 27, 2026