R52.0 R52.2 F05.8
Conditions
Interventions
Group 1: Patients undergoing elective surgery under total intravenous general anesthesia are included.
The reaction to painful and non-painful measures is observed before, during and after anesthesia.
Sponsors
Klinik für Anästhesie, Intensiv-, Notfall- und Schmerzmedizin
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 2. patients with an ASA status I to III (according to the American Society of Anesthesiologists) 3. planned elective surgery under total intravenous general anesthesia (TIVA) 4. planned securing of the airway by tracheal intubation 5. ability to give written informed consent 6. presence of written informed consent
Exclusion criteria
Exclusion criteria: 1. required rapid sequence induction 2. taking antipsychotics and antidepressants 3. chronic pain disorder with current opioid medication 4. inability to answer the preoperative questionnaire unaided 5. pre-existing pupillary anomaly or condition after pupil-altering eye surgery 6. BMI >35 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. chronic postoperative pain | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. acute postoperative pain 3. postoperative consumption of painkillers 4. postoperative delirium 5. postoperative increase of stress hormones in the blood 6. clinical responses to nociceptive and non-nociceptive stimulation during induction of anesthesia 7. clinical responses to nociceptive and non-nociceptive stimulation during anesthesia maintenance 8. clinical responses to nociceptive and non-nociceptive stimulation during emergence from anesthesia | — |
Countries
Germany
Contacts
Public ContactFalk von Dincklage
Klinik für Anästhesie, Intensiv-, Notfall- und Schmerzmedizin
Outcome results
None listed