Alterations of the gut microbiome in patients with IBS in correlation to illness anxiety and symptom severity

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00033141

Enrollment

Registered

2023-12-18

Start date

2023-04-11

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K58 F45.32

Interventions

Group 1: This cross-sectional study includes patients with irritable bowel syndrome (IBS). Patients are asked for a stool sample and to fill in a set of questionnaires. Questionnaires include: ROME-IV

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Irritable Bowel Syndrome in the clinical assessment Irritable Bowel Syndrome according to the Rome-IV-Criteria Signed informed consent

Exclusion criteria

Exclusion criteria: Chronic inflammatory bowel disease Severe psychopathologies such as acute suicidality or current substance dependence Recent use of antibiotics within the past two weeks

Design outcomes

Primary

Measure	Time frame
Description of patients with irritable bowel syndrome	—

Secondary

Measure	Time frame
Interactions between the composition of the gut microbiome and the severity of IBS symptoms (IBS-SSS), illness anxiety (WI-7) and further psychosocial factors.	—

Countries

Germany

Contacts

Public ContactFelicitas Engel

Universitätsklinikum Heidelberg, Abteilung für Allgemeine Innere Medizin und Psychosomatik

felicitas.engel@med.uni-heidelberg.de+49 6221 56 0

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026