Bile acids in critically ill patients with hyperbilirubinemia and the correlation with static and dynamic liver function tests

Bile acids in critically ill patients with hyperbilirubinemia and the correlation with static and dynamic liver function tests - UGIL

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00033123

Enrollment

200

Registered

2023-12-18

Start date

2024-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K72

Interventions

Group 1: In intensive care patients with hyperbilirubinemia (>3mg/dl), clinical and laboratory data are collected, an abdominal ultrasound is performed to examine liver perfusion and a LiMON measureme

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age of majority Total bilirubin > 3 mg/dl

Exclusion criteria

Exclusion criteria: Patients who or their legal guardians have not consented to the study Patients after liver transplantation Death likely within 48 hours of inclusion Chronic liver function impairment with bilirubin >3mg/dl prior to acute illness No planned LiMON® measurement in clinical routine Postoperative after liver transplantation

Design outcomes

Primary

Measure	Time frame
Investigation of a possible correlation of bile acid concentrations and liver function in intensive care patients with hyperbilirubinemia.	—

Secondary

Measure	Time frame
Creation of a bile acid profile of intensive care patients and investigation of the correlation with certain underlying and previous illnesses.	—

Countries

Germany

Contacts

Public ContactCaroline Gräfe

LMU Klinikum München, Klinik für Anaesthesiologie

Caroline.Graefe@med.uni-muenchen.de+4989440081225

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 9, 2026