Microstructure modelling using enhanced diffusion-weighted magnetic resonance imaging for non-invasive prostate cancer diagnostics - a feasibility study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00033122

Enrollment

300

Registered

2023-12-29

Start date

2023-12-04

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C61

Interventions

Group 1: For men with suspected prostate cancer and an indication for an MRI, additional MRI sequences are included in the standard protocol. With the help of these new sequences, mathematical microst

Eligibility

Sex/Gender

Male

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - patients are scheduled for an mpMRI examination due to suspected prostate carcinoma

Exclusion criteria

Exclusion criteria: - patients have a contraindication for an MRI scan AND - patients have had previous radiotherapy of the prostate, hormone therapy, previous TUR-P or other prostate surgery AND - patients lack willingness, ability and capacity to consent

Design outcomes

Primary

Measure	Time frame
Sensitivity, specificity and receiver operating characteristic (ROC) curve of the different biophysical models for the diagnosis of clinically significant prostate cancer	—

Secondary

Measure	Time frame
Comparison with PI-RADS classification and existing biopsy results	—

Countries

Germany

Contacts

Public ContactAndreas Bartsch

Radiologie Bamberg

andreas.bartsch@radiologie-bamberg.de0951980300

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026