G91.9
Conditions
Interventions
Group 1: Transorbital and transtemporal ultrasound during an external ventricular drainage (EVD) weaning attempt
Sponsors
Universitätsmedizin Göttingen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Planned EVD weaning trial Acute subarachnoid hemorrhage (SAH) or Acute intracerebral hemorrhage with ventricular collapse or Meningitis/encephalitis or Acute cerebral edema or Severe TBI (typically GCS 3-8)
Exclusion criteria
Exclusion criteria: Age < 18 years Decompressive hemicraniectomy Acute injuries to one and/or both eyes in which further damage cannot be reliably ruled out by the ONSD measurement (even with compliant device settings). Z.n. Operations in the area of the orbit or N. II, which could influence the measurement result Chronic inflammatory changes in the II nerve (e.g. multiple sclerosis) Chronic ICP elevation (e.g. pseudotumor cerebri) Chronic hydrocephalus syndromes Chronic CSF hypotension syndromes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EVD-Weaning failure | — |
Secondary
| Measure | Time frame |
|---|---|
| Optic nerve sheath diameter (ONSD) after 24 hours, change in ONSD from initial measurement and after 24 hours, CT/MR imaging: width of the 3rd ventricle; Evan’s index, parieto-occipital ratio (POR) and temporal ratio (TR) | — |
Countries
Germany
Contacts
Public ContactIlko Maier
Universitätsmedizin Göttingen
Outcome results
None listed