Overweight/Obesity
Conditions
Interventions
Group 1: Control with 75 g Glucose and 150 mg 13C-Na-Acetate
Group 2: Intervention with 75 g Glucose, 150 mg 13C-Na-Acetate and 15 g of pea protein hydrolysates type 1 (EH1)
Group 3: Intervention with
Sponsors
Leibniz-Institut für Lebensmittel-Systembiologie
Eligibility
Sex/Gender
Male
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: -20-45 years -Written declaration of consent -Men -Non-smoker -No chronic drug treatment -BMI 25-30 kg/m2
Exclusion criteria
Exclusion criteria: - Female subjects, due to the effect of cycle-related fluctuations on satiety hormones - Smoker - Current participation in another intervention study - Diseases affecting nutrient absorption, digestive function, metabolism or excretion - Acute infectious diseases - Chronic illnesses according to medical history (e.g. hepatitis B and C, diabetes mellitus) - Gastrointestinal complaints - History of diverticulosis, constipation - Intolerance or allergy to any component of the intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determination of the subjects' subjective feeling of hunger before and after administration of the hydrolysates in each intervention arm by using visual analogue scales. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Determination of the subjects' energy intake with a subsequent ad libitum breakfast by using optiDiet in each intervention arm - Examination of gastric emptying with the aid of a 13C-Na-acetate breath test in each intervention arm - Determination of blood plasma concentrations of the hormones ghrelin, serotonin, GLP 1, CCK, insulin, and plasma glucose in each intervention arm - Sensory test to determine the individual bitter threshold value by using questionnaires | — |
Countries
Germany
Contacts
Public ContactVeronika Somoza
Leibniz-Institut für Lebensmittel-Systembiologie
Outcome results
None listed