Patients with cardiosurgical proceddure including 1-2h of HLM use, e.g. aortocoronary bypass operations or aortic valve operations
Conditions
Interventions
Group 1: No mechanical ventilation (only PEEP) of the lung during use of HLM in cardiac surgery
Group 2: Lung ventilation (including PEEP as in arm1) during the use of HLM in cardiac surgery
Sponsors
Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Elektiv cardial surgery OP with sternotomy and clamping of the aorta. ASA status < V written informed consend
Exclusion criteria
Exclusion criteria: pregnancy, case of emergency, increased risk of aspiration, treated pneumonia, GOPD GOLD = 4, Language barrier excluding informed consent. Cases in which surgery time is prolonged > 60 min or require stop of lung ventilation > 10 min in the ventilation group for surgical reasons will be excluded from data analyses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of nonlinear respiratory system compliance between start and end of surgical procedure. Calculations will be based on the pressure and flow curves, measured at the ventilator. | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of intraoperative compliance profiles, frequencies of postoperative pulmonary complications (O2 required, atelectasis, pneumonia), vitalparameters of monitoring: ECG, arterial blood pressures, paO2, paCO2, SaO2, etCO2 in course. | — |
Countries
Germany
Contacts
Public ContactStefan Schumann
Universitätsklinikum Freiburg
Outcome results
None listed