Effects of multimodal inpatient complex therapy in former COVID-19 patients with post-Covid syndrome - a retrospective study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00033018

Enrollment

Registered

2023-11-13

Start date

2023-09-30

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-Covid syndrome

Interventions

Group 1: Inpatients who received multimodal complex therapy for the treatment of post-Covid syndrome (PCS). The therapy comprised conventional and integrative therapy approaches, including hyperthermi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Inpatient admission to the Paracelsus Hospital in Unterlengenhardt for the treatment of post-Covid syndrome 2. Diagnosis of post-Covid syndrome 3. Verbal informed consent to complete the questionnaires

Exclusion criteria

Exclusion criteria: Serious comorbidities that produce symptoms similar to post-Covid syndrome and therefore make it difficult to monitor treatment outcome, in particular: - Advanced oncological diseases with cancer-related fatigue - Advanced respiratory diseases with dyspnoea - Advanced cardiovascular diseases with dyspnoea and/or fatigue - Advanced neurological diseases with cognitive dysfunction and/or fatigue - Symptomatic endocrine diseases, e.g. hypothyroidism, with fatigue Insufficient German language skills to complete the questionnaires

Design outcomes

Primary

Measure	Time frame
Change in the sum score of the FACIT fatigue scale (FACIT-F, Functional Assessment of Chronic Illness Therapy - Fatigue) between the values on admission to hospital and four weeks after discharge (follow-up)	—

Secondary

Measure	Time frame
- Change in the Fatigue Impact Scale sum score (FIS) between the values on admission to hospital and four weeks after discharge (follow-up) - Change in the Multidimensional Dyspnoea Profile sum score (MDP) between the values on admission to hospital and four weeks after discharge (follow-up) - Other symptoms such as insomnia, depression, pain, loss of appetite and post-exertional malaise (PEM), recorded using a self-developed questionnaire ("Questionnaire on Covid-associated symptom burden" with 12 items, score for each symptom complex from 0 = no symptoms to 4 = very severe symptom burden)	—

Measure

Time frame

- Change in the Fatigue Impact Scale sum score (FIS) between the values on admission to hospital and four weeks after discharge (follow-up) - Change in the Multidimensional Dyspnoea Profile sum score (MDP) between the values on admission to hospital and four weeks after discharge (follow-up) - Other symptoms such as insomnia, depression, pain, loss of appetite and post-exertional malaise (PEM), recorded using a self-developed questionnaire ("Questionnaire on Covid-associated symptom burden" with 12 items, score for each symptom complex from 0 = no symptoms to 4 = very severe symptom burden)

—

Countries

Germany

Contacts

Public ContactThomas Breitkreuz

Paracelsus-Krankenhaus Unterlengenhardt,

t.breitkreuz@paracelsus-krankenhaus.de+49 7052 925 1160

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026