T13.03
Conditions
Interventions
Group 1: One sting per patient is treated thermally with the BR 60 insect sting healer.
Group 2: One sting per patient remains untreated.
Sponsors
Institut Kurscheid
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Consent to the study - >18 years - Knowledge of own reaction to insect bites - Willingness to be bitten twice by the two mosquito strains laboratory strains
Exclusion criteria
Exclusion criteria: - Allergies to insect bites - Acute skin diseases in the region - Acute illnesses (especially with a tendency to thromboembolic diseases and malignant neoplasms) - Chronic pain conditions that have not been clarified, regardless of the body region - Diabetes - Sensitivity disorder with reduced pain sensation (e.g. metabolic disorder)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in pruritus severity between treated and untreated prick on a 10-point VAS score over 1 hour (AUC) | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference in pruritus severity between treated and untreated bites on a 10-point VAS score over 1 hour (AUC) Yellow fever mosquito (Aedes aegypti) and southern house mosquito (Culex quinquefasciatus) (10 patients) - Difference in pruritus severity between treated and untreated bites on a 10-point VAS score at the time points 2, 7, 11, 15, 40, 60 minutes (AUC) for all mosquitoes and each individual mosquito - Difference in swelling between treated and untreated bite on a 10-point VAS score over 1 hour (AUC) - Difference in redness between treated and untreated bite on a 10 point VAS score over 1 hour (AUC) | — |
Countries
Germany
Contacts
Public ContactSergej Sperling
Biogents AG
Outcome results
None listed