Harmful alcohol use ( AUDIT score >16)
Conditions
Interventions
Group 1: Alcohol Group (recruited based on AUDIT total score > 15)
alcohol use is assessed using the AUDIT questionnaire and habit formation is tested using different behavioural methods.
Group 2: Cannabis Group (recruited based on CUDIT-R total score > 13)
cannabis use is assessed using the CUDIT-R questionnaire and habit formation is tested using different behavioural methods.
Group 3: Healthy Control Group (AUDIT < 10
CUDIT-R < 6)
habit formation is tested using different behavioural methods.
Sponsors
University of Cambridge
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Good/stable physical and mental health Normal body weight (BMI > 18 and <30)
Exclusion criteria
Exclusion criteria: Group-specific exclusion criteria (one of the following descriptions applies): o Regular use of alcohol over the recommended limits (AUDIT score >16) – alcohol group o Regular use of cannabis (CUDIT-R score >13) – cannabis group o No use of drugs and alcohol only within recommended limits (AUDIT score < 8, CUDIT-R <1) – control group Exclusion criteria (for all participants): • A personal history of substance use disorder • A personal history of a neurological, or neurodevelopmental disorder • A history of a head or brain trauma • Severe physical impairments affecting eyesight or motor performance •Insufficient proficiency of English to provide informed consent and to understand task instructions • Any serious medical disorder or condition that would in the investigator’s opinion preclude participation in the study. • Current psychoactive medication (e.g., antidepressants) - controls only
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Goal-directed/habit ratio measured by different behavioural tests (e.g. Slip of Action score) and questionnaire responses (e.g. COHS - creature of habit scale). | — |
Secondary
| Measure | Time frame |
|---|---|
| Optimal responses in social situations, as reflected by the number of cooperative decisions. | — |
Countries
United Kingdom
Contacts
Public ContactKaren Ersche
University of Cambridge
Outcome results
None listed