Nutritional immunity – adaptation or maladaptation in sepsis?

Nutritional immunity – adaptation or maladaptation in sepsis? - SIMRI 2.0

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032956

Enrollment

150

Registered

2023-11-03

Start date

2024-02-27

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis A41.9

Interventions

Group 1: The aim of this study is to investigate the time- and course-specific iron distribution during sepsis, also with regard to the effect of foreign blood transfusions. To be investigated are mar

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosis "sepsis" according to sepsis 3 definition

Exclusion criteria

Exclusion criteria: - Pregnancy - Inclusion in an interventional study - Infectious viral diseases (HBV, HCV, HIV, COVID-19) - Iatrogenic immunosuppression - Diagnosis of "sepsis" > 24 h

Design outcomes

Primary

Measure	Time frame
time- and course-specific iron distribution during sepsis	—

Secondary

Measure	Time frame
Polarization and activity of immune cells	—

Countries

Germany

Contacts

Public ContactDania Fischer

Universitätsklinikum Heidelberg

dania.fischer@med.uni-heidelberg.de06221-56-36166

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026