Influence of maximal bicycle ergometric exercise on extracellular inflammasome particles and cardiac parameters in athletes.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032941

Enrollment

Registered

2023-11-30

Start date

2023-12-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress-dependent adaptation processes

Interventions

Group 1: No intervention, observational, 50 athletes with regular competition participation linked to regular care at the university hospital via the sports cardiology outpatient clinic. Blood sample

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: regular sport activity with competition

Exclusion criteria

Exclusion criteria: Known underlying pulmonary or cardiac disease defined as. Heart failure with preserved or reduced pump function, Myocarditis, known coronary artery disease, obstructive restrictive lung disease. Lack of consent Pregnancy

Design outcomes

Primary

Measure	Time frame
NLRP3 - inflammasome, inflammatory parameters, cardiac enzymes, haemogram, renal parameters	—

Secondary

Measure	Time frame
CPET (VO2peak, HFpeak, O2 pulse, Ppeak, lactate) Impedance cardiography (cardiac output, stroke volume, CI, avDO2) Echocardiography (GLS, GWI )	—

Countries

Germany

Contacts

Public ContactSven Fikenzer

Universitätsklinikum Leipzig

sven.fikenzer@medizin.uni-leipzig.de+49 341 97 12650

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 9, 2026