GFAP and UCH-L1 in SAB

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032939

Enrollment

Registered

2023-11-06

Start date

2023-08-31

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I60.7

Interventions

Group 1: 50 Patients with aneurysmal subarachnoid hemorrhage, Measurement of the biomarkers GFAP and UCH-L1 in serum in the first two weeks after the SAB, correlation of the increases in the two bioma

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Aneurysmal SAB, Informed consent for the research project, Voluntary participation

Exclusion criteria

Exclusion criteria: Refusal by patient or legal guardian or health care proxy, withdrawal of consent given, pregnancy, bleeding event more than 24 hours before admission to ICU 91

Design outcomes

Primary

Measure	Time frame
Is there a statistically significant correlation of an increase in both biomarkers GFAP and UCH-L1 with delayed cerebral ischemia after SAB, diagnosed by means of the diagnostic capabilities available to date.	—

Secondary

Measure	Time frame
Is either one biomarker or a combination of both biomarkers more suitable for the detection of delayed cerebral ischemia.	—

Countries

Germany

Contacts

Public ContactJohanna Rosenberger

Universitätsklinikum Regensburg

johanna.rosenberger@ukr.de+499419440

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026