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Prospective analysis of clot stability and hyperfibrinolysis before and during liver transplantation using viscoelastometric tests and investigation of their predictive value with regard to intraoperative transfusion volumes and thromboembolic complications.

Prospective analysis of clot stability and hyperfibrinolysis before and during liver transplantation using viscoelastometric tests and investigation of their predictive value with regard to intraoperative transfusion volumes and thromboembolic complications.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00032827
Enrollment
30
Registered
2023-10-06
Start date
2023-09-23
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver transplantation K72

Interventions

Group 1: Coagulation analysis by viscoelastometry in patients during liver transplantation. Measurements are taken before the start of surgery, immediately at the start of the anhepatic phase, at the

Sponsors

LMU Klinikum
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Patients for orthotopic liver transplantation - Consent of patient or caregiver - Age > 18 years

Exclusion criteria

Exclusion criteria: - Refusal of the patient or caregiver. - Age < 18 years - Stop of the operation, e.g. due to rejection of the organ

Design outcomes

Primary

MeasureTime frame
Detection of hyperfibrinolysis by viscoelastometry (EX-test and ECA-test) at the described measurement time points (before the start of surgery, immediately at the start of the anhepatic phase, at the end of the anhepatic phase, 10min after reperfusion, and at the end of surgery).—

Secondary

MeasureTime frame
1. Time to detection of hyperfibrinolysis. 2. Correlation of preoperative viscoelastometric variables with transfusion volumes 3. Correlation of preoperative coagulation factor concentrations with bleeding volumes 4. Correlation of viscoelastometric variables with occurrence of thromboembolic events within 7 days postoperatively.—

Countries

Germany

Contacts

Public ContactPhilipp Groene

LMU Klinikum

philipp.groene@med.uni-muenchen.de0890440081189

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 7, 2026