Prospective Validation of Radiomics models for evaluation of molecular biomarkers in patients with cerebral metastasis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032787

Enrollment

200

Registered

2023-11-16

Start date

2023-12-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C79.3

Interventions

Group 1: For analysis the preoperative MRI scan of the brain is used. Further acquired parameters: histopathological result, age, sex, Karnofsky Performance Score, oncological therapy

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: brain metastasis available preoperative MRI interdiciplinary tumor board decision for surgery or biopsy of the brain metastasis

Exclusion criteria

Exclusion criteria: Previous local therapy for brain metastases

Design outcomes

Primary

Measure	Time frame
Validation of Radiomics models for prediction of molecular biomarkers in patients with brain metastases.	—

Secondary

Measure	Time frame
Evaluation of the biological meaning of the acquired radiomics signatures.	—

Countries

Germany

Contacts

Public ContactAnna-Katharina Meißner

Zentrum für Neurochirurgie, Universitätsklinik Köln, Medizinische Fakultät, Universität zu Köln

anna-katharina.meissner.@uk-koeln.de+221 478 82796

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026