Biomarkers to differentiate asymptomatic bacteriuria into urinary tract infection or colonization requiring treatment

Biomarkers to differentiate asymptomatic bacteriuria into urinary tract infection or colonization requiring treatment - MetaBio

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032772

Enrollment

100

Registered

2023-10-13

Start date

2025-10-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N39.0

Interventions

Group 1: Female patients with acute urinary tract infection

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: - Female gender, premenopausal - Symptomatic, community-acquired, uncomplicated urinary tract infection; defined according to the criteria of the current AWMF guideline (4) BEFORE antibiotic therapy. - Written informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: - Evidence of more serious or other urogenital infection including fever, flank pain, renal pelvic palpitation, vaginal discharge, and vaginal pain. - Pregnancy - Diabetes mellitus and other relevant metabolic diseases - Kidney disease - Taking medications that affect the genitourinary tract - Immunosuppression

Design outcomes

Primary

Measure	Time frame
Differences in metabolome composition between patients with acute symptomatic UTI and healthy subjects.	—

Secondary

Measure	Time frame
Difference in intra- and interindividual metabolome composition of the subjects under predefined preanalytical conditions compared to the preanalytical best practice protocol defined as gold standard	—

Countries

Germany

Contacts

Public ContactJulia Koepsell

Universitätsklinikum Frankfurt

julia.koepsell@kgu.de+49 6301 6384

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 9, 2026