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Characterization of bioactive lipids in selected immune cell populations of leukemia patients and their influence on disease progression: a clinically prospective lipidomics approach

Characterization of bioactive lipids in selected immune cell populations of leukemia patients and their influence on disease progression: a clinically prospective lipidomics approach

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00032698
Enrollment
120
Registered
2024-06-05
Start date
2024-02-21
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myeloid leukemia and acute lymphocytic leukemia

Interventions

Group 1: Adult patients with newly diagnosed acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL) who actively declare their participation in the study and are not eligible for stem cell

Sponsors

Carl von Ossietzky Universität Oldenburg, Fakultät VI, Abt. Pharmakologie & Toxikologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with newly diagnosed AML and ALL who have actively consented to the study.

Exclusion criteria

Exclusion criteria: The following patients are excluded: Children, persons who are unable to give consent to the study, pregnant women, patients treated exclusively in palliative care and patients who receive or actively seek a hospice place as well as patients after bone marrow transplantation and under CAR-T cell therapy

Design outcomes

Primary

MeasureTime frame
Detection of statistically significant differences in the concentration of bioactive lipid species between leukemia patients and healthy control groups.

Secondary

MeasureTime frame
Identification of statistically significant differences in PCR and Western blot analyzes in selected immune cell populations in dependency to lipid-associated proteins.

Countries

Germany

Contacts

Public ContactBernhard Rauch

Carl von Ossietzky Universität Oldenburg, Fakultät VI, Abt. Pharmakologie & Toxikologie

bernhard.rauch@uni-oldenburg.de+49 441 798 4930

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 27, 2026