Tumors, vascular diseases, neurodegenerative diseases
Conditions
Interventions
Group 1: Magnetic resonance imaging (MRI) examinations that are performed as part of the clinical routine and are clinically indicated are supplemented by an additional modified standard sequence ("GE
Sponsors
Uniklinikum RWTH Aachen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The patients are examined as part of a clinically indicated MRI examination (clinical routine). In principle, all patients with the above-mentioned clinical pictures who are suitable for MRI examinations can be included. MRI examination to clarify a disease from the following types: • Vascular diseases (e.g. stenosis of the arteries supplying the brain) • Tumor diseases (e.g. brain tumors) • Neurodegenerative diseases (e.g. Alzheimer's disease) • Inflammatory, metabolic or immunological diseases (e.g. multiple sclerosis) • Malformations (e.g. schizencephaly) • Trauma (e.g. condition after traumatic brain injury)
Exclusion criteria
Exclusion criteria: Patients under the age of 18 are excluded. Patients who cannot undergo a routine MRI examination due to contraindications cannot participate in the study. These are patients who carry certain electrical devices (e.g. pacemakers, drug pumps, etc.) or certain metal parts (e.g. screws after bone fractures) in or on the body and/or patients who suffer from claustrophobia. Pregnancy (exclusion by means of a urine test) Patients whose examination would require additional time, which could delay any necessary acute therapy, are also excluded from participation in the study. Patients for whom prolonged lying in the scanner is a burden (e.g. due to back problems or restlessness). Patients who are deprived of their liberty on the basis of an official or court order or authorization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of the research project is to compare OEF values in the various pathologies with healthy values in order to characterize possible dependencies and changes. The healthy contralateral hemisphere can serve as an intraindividual comparison. The comparison to healthy individuals can (subsequently) also be made using among others values from the literature. | — |
Countries
Germany
Contacts
Public ContactDimah Hasan
Uniklinik RWTH Aachen
Outcome results
None listed