Improving visual performance in retinitis pigmentosa by new non-invasive personalized and adaptive training

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00032628

Enrollment

Registered

2023-09-07

Start date

2022-06-09

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICD-10 H35.52 - Pigmentary retinal dystrophy

Interventions

Group 1: Arm 1: Intervention by virtual reality gaze training followed by a control phase

evaluation of the training results as well as results of the control phase in three additional sessions in an experimental environment (training phase: 20 training sessions of 30 minutes each distribu

control phase: 4 weeks without intervention

3 sessions in experimental environment 120 minutes). Group 2: Arm 2: Same as arm 1, but the training phase takes place after the control phase

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Visual Field diameter between 5° and 30°; Visual Acuity of 0.1 or more in both eyes; no mobility restrictions

Exclusion criteria

Exclusion criteria: Visual Field diameter not between 5° and 30°; Visual Acuity lower than 0.1; restricted mobility; secondary ophthalmic conditions (individually determined based on type and severeness of the condition)

Design outcomes

Primary

Measure	Time frame
WHAT Navigation performance (walking speed and obstacle avoidance) + visual performance (dynamic visual field during navigation) WHEN for arm 1: T1 immediately before training phase T2 immediately after training phase and immediately before control phase T3 immediately after control phase for arm 2: T1 immediately before control phase T2 immediately after control phase and immediately before training phase T3 immediately after training phase HOW Setup of a randomized obstacle course in an experimental environment, 20 trials per session (T1, T2, T3) and per subject; evaluation of the dynamic visual field through eye-tracking	—

Measure

Time frame

WHAT Navigation performance (walking speed and obstacle avoidance) + visual performance (dynamic visual field during navigation) WHEN for arm 1: T1 immediately before training phase T2 immediately after training phase and immediately before control phase T3 immediately after control phase for arm 2: T1 immediately before control phase T2 immediately after control phase and immediately before training phase T3 immediately after training phase HOW Setup of a randomized obstacle course in an experimental environment, 20 trials per session (T1, T2, T3) and per subject; evaluation of the dynamic visual field through eye-tracking

—

Secondary

Measure	Time frame
Qualitative evaluation of the developed training method by individual questionnaire; the questionnaire consists of questions according to 10-point Likert scale format as well as questions with free-form answering option	—

Countries

Germany

Contacts

Public ContactSiegfried Wahl

Forschungsinstitut für Augenheilkunde, Universitätsklinik Tübingen

siegfried.wahl@uni-tuebingen.de+49 7071 29-84512

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026