Validation of non-radiative MRI-based multi-atlas attenuation correction for single-photon emission computed tomography

Validation of non-radiative MRI-based multi-atlas attenuation correction for single-photon emission computed tomography - MRI-based attenuation correction for SPECT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032584

Enrollment

Registered

2023-09-26

Start date

2023-11-30

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20.0

Interventions

Group 1: Recording of a low-dose computed tomography (CT) of the head

Eligibility

Sex/Gender

All

Age

50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Parkinson’s Disease (Hoehn and Yahr <3) 2. Participant of the DoMoCo study who previously gave consent that they can be contacted in the future for scientific purpose 3. DAT-SPECT at the Department of Nuclear Medicine for diagnostic purpose 4. Compatible MRI as part of DoMoCo study 5. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Any radiation exposure in the recent 10 years for scientific or therapy purposes 2. Pregnancy/breast feeding 3. Severe physical illness/physical conditions 4. Claustrophobia or excessive overweight

Design outcomes

Primary

Measure	Time frame
The aim of the study: Validation of an MRI-based attenuation correction for the evaluation of the 123I-FP-CIT signal in the brain by comparison with a CT-based attenuation correction.	—

Countries

Germany

Contacts

Public ContactMerle Hönig

Uniklinik Köln, Klinik für Nuklearmedizin

merle.hoenig1@uk-koeln.de+49-221-478 82837

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026