G20
Conditions
Interventions
Group 1: stimulation off
Group 2: stimulation at the theta frequency (6 Hz)
Group 3: stimulation at the beta frequency (15 Hz)
Group 4: stimulation at the low gamma frequency (70 Hz)
Group 5: stimulat
Sponsors
University Hospital Giessen and Marburg
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: - Confirmed diagnosis of idiopathic Parkinson's syndrome - Implanted THS electrode in the Department of Neurosurgery of the UKGM Marburg (target area: STN) - German as mother tongue - Right-handedness - Duration of implantation longer than three months - Willingness to participate in EEG examinations - Ability to understand the subject information and to give written consent - Written consent for voluntary participation in the study
Exclusion criteria
Exclusion criteria: - Central neurological or severe psychiatric disease - Presence of atypical or secondary parkinsonian syndrome - Prior CNS surgery other than THS implantation. - Mild Cognitive Impairment (MCI, PANDA, see Appendix 3)) - Regular use of medications affecting the CNS that have not been discontinued the evening before the examination until after the examination. - Severe, non-compensable hearing or visual impairment - Chronic alcohol or drug abuse in the past two years - Pregnancy or lactation - Legal incapacity - Court-ordered or government-ordered institutionalization - Only in the case of obtaining new MRI scans: Common MRI exclusion criteria (cardiac pacemaker, implanted ferromagnetic objects, non-MRI compatible THS electrode)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Working memory performance measured by a modified Sternberg task | — |
Countries
Germany
Contacts
Public ContactCarina Oehrn
University Hospital Giessen and Marburg
Outcome results
None listed