intraoIntraoperative nociception and patient outcome Investigation of the NOL (Nociception Level Index) in patients with surgical, urological, gynecological, or orthopedic/trauma surgery procedures under general anesthesiaperative nociception and patient-outcome

intraoIntraoperative nociception and patient outcome Investigation of the NOL (Nociception Level Index) in patients with surgical, urological, gynecological, or orthopedic/trauma surgery procedures under general anesthesiaperative nociception and patient-outcome - NOL-Survey

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032578

Enrollment

Registered

2024-01-17

Start date

2024-01-16

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R52

Interventions

Group 1: Monocentric observational study Patients after a surgical procedure under general anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Consenting adults (age = 18) - signed declaration of consent - planned surgical intervention under general anesthesia

Exclusion criteria

Exclusion criteria: - insufficient knowledge of German - Surgery under regional anesthesia - Current pregnancy - Patient is confused/has difficulties in understanding - Cardiac arrhythmias (including absolute arrhythmia in atrial fibrillation, pacemaker-dependent patients)

Design outcomes

Primary

Measure	Time frame
The primary objective of the study is to analyze the association between intraoperative nociception (Nociception Level Index, NOL index; PMD200, Medasense Biometrics Ltd.) and patient outcome (pain intensity, pain interference, side effects) as a composite score on postoperative day 1	—

Secondary

Measure	Time frame
Influence of intraoperative nociception on chronic postoperative pain (FU 3 months, FU 6 months). Individual domains of the QUIPS questionnaire (pain intensity, impairment, side effects)	—

Countries

Germany

Contacts

Public ContactClaudia;Winfried Neumann;Meißner

Uniklinikum Bonn;Uniklinikum Jena

claudia.neumann@ukbonn.de;winfried.meissner@med.uni-jena.de+49 (0) 228 287-14114;

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026