Diagnosis of bacteremia in suspected sepsis using functionalized iron oxide nanoparticles

Diagnosis of bacteremia in suspected sepsis using functionalized iron oxide nanoparticles - Nanoparticle-based pathogen diagnostics

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00032571

Enrollment

500

Registered

2023-09-11

Start date

2023-11-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A41.9

Interventions

Group 1: Patients with existing or suspected sepsis or a severe infection. An additional blood tube ( 9 ml) is taken as part of the routine blood collection.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult male or female patients who are capable of giving consent

Exclusion criteria

Exclusion criteria: - Patients who refuse to give consent to sample collection or are incapable of giving consent. - Patients in whom blood cultures cannot be taken (e.g. due to unfavourable vascular conditions).

Design outcomes

Primary

Measure	Time frame
Time to pathogen identification using nanoparticle-based diagnostics versus conventional blood culture diagnostics in patients with suspected sepsis or severe infection.	—

Secondary

Measure	Time frame
- Species identification of cultivated germs by MALDI-TOF analysis. - Time from blood collection to detection, identification and resistance testing - Categorical results and minimum inhibitory concentrations of resistance testing	—

Countries

Germany

Contacts

Public ContactChristoph Alexiou

Universitätsklinikum Erlangen

christoph.alexiou@uk-erlangen.de+4991318533142

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026