Q77.4
Conditions
Interventions
Group 1: People with achondroplasia in the age range of 6-18 years.
The observation period is 2 1/2 years with half-yearly measurement dates. Follow-up measurements are not planned.
Group 2: Typical d
Sponsors
Otto-von-Guericke-Universität Magdeburg, Institut III
Eligibility
Sex/Gender
All
Age
6 Years to 18 Years
Inclusion criteria
Inclusion criteria: Achondroplasia Group: - A parent or legal guardian who signs the consent form and the subjects information for the subject. - Clinical diagnosis of achondroplasia by the Faculty of Medicine/University Hospital A.ö.R. (FME/UKMD) University Children's Hospital (KPAE) (Dr. Palm) - An age between 6 to 18 years - The ability to walk barefoot independently without an assistive device - Current medical treatment of e.g. vosoritides, orthopedic interventions) or human growth hormones or other medical products that have the intention of influencing body size or body disproportions will be documented at all time points Control group: - A parent or legal guardian who will sign the informed consent form and subject information form for the subject - The ability to follow the test protocol as judged by a member of the measurement team. - An age between 6 to 18 years - Corrected or near normal corrected vision
Exclusion criteria
Exclusion criteria: Achondroplasia Group: - Skeletal dysplasias other than achondroplasia or medical conditions resulting in decreased body size or abnormal bone growth - Dependence on orthotics or assistive devices for locomotion - Hemieepophysiodesis (< 3 months) - Lengthening of extremities/ osteotomy with full recovery are included with a minimum healing time of 12 months - Past or present injury or disease to the growth plate(s), other than ACH, that affects the growth potential of the bones - Decompression of the foramen magnum and a laminectomy with a complete recovery are allowed with a minimum healing time of 6 months. Control group: - Past lower extremity injuries within the last six months that required medical treatment. - Past orthopedic treatments - History of toe walking - Any foot deformities that required conservative or invasive treatment in the past - Any evidence of neurological abnormalities - Suspected or diagnosed developmental coordinative disorders - Chronic cardio-vascular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kinematic and kinetic gait parameters were collected with the ViconNexus system. | — |
Secondary
| Measure | Time frame |
|---|---|
| Static balance surveyed with AMTI force plates and quality of life assessed by the following questionnaires: - APLES (The Achondroplasia Personal Life Experience Scale). - Qolissy (Quality of life in adolescents of short stature) | — |
Countries
Germany
Contacts
Public ContactKerstin Witte
Otto-von-Guericke-Universität Magdeburg, Institut III
Outcome results
None listed