Thrombus characterization using MRI in intermediate-high-risk patients with pulmonary embolism and catheter-based interventional treatment

Thrombus characterization using MRI in intermediate-high-risk patients with pulmonary embolism and catheter-based interventional treatment - TIHLE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032538

Enrollment

100

Registered

2024-01-23

Start date

2024-01-23

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I26.0

Interventions

Group 1: Intermediate-high risk PE patientes

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.) Age from 18 years up to and including 85 years 2.) Confirmed acute pulmonary artery embolism using CTPA (computed tomographic pulmonary angiography) 3.) Diameter ratio between right and left ventricles (RV/LV) = 1 in CT scan or echocardiography 4.) Concentration of troponin T above the detection limit 5.) PESI Score III-V

Exclusion criteria

Exclusion criteria: 1.) Hemodynamic instability 2.) Pregnancy or breastfeeding 3.) Low-risk pulmonary artery embolism 4.) Earlier inclusion in the study

Design outcomes

Primary

Measure	Time frame
Thrombus age depending on the T1 relaxation time in MRI and histology	—

Secondary

Measure	Time frame
RV/LV ratio, TAPSE, oxygen saturation, blood pressure, heart rate	—

Countries

Germany

Contacts

Public ContactMarcus Brugger

Klinikum rechts der Isar der Technischen Universität München

marcus.brugger@tum.de+49 89 4140 2350

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026