All patients who underwent surgery for malignant or benign pancreatic disease in the years 2001 to 2019 in the Department of General and Visceral Surgery at Freiburg University Hospital and have fully documented preoperative diagnostics, laboratory parameters, postoperative course were included. All entities that have received pancreatoduodenectomy will be considered.
Conditions
Interventions
Group 1: All patients who underwent surgery for malignant or benign pancreatic disease in the years 2001 to 2019 in the Department of General and Visceral Surgery at Freiburg University Hospital and h
Sponsors
Uniklinik Freiburg, Department für Allgemein- und Viszeralchirurgie
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who have undergone surgery for a malignant or benign disease of the pancreas in the years 2001 to 2019 in the Department of General and Visceral Surgery at Freiburg University Hospital and have fully documented preoperative diagnostics, laboratory parameters and postoperative course are eligible for inclusion. All entities that have undergone pancreatoduodenectomy will be considered.
Exclusion criteria
Exclusion criteria: None.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of sensitivity, specificity, positive-predictive value, and negative-predictive value of various preoperative laboratory parameters and preoperative pancreatic ductal width using radiologic imaging for early detection of POPF risk. Evaluation of pancreatic parenchymal fibrosis and POPF rate in patients with and without elevated tumor marker CA-19-9. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of the other possible risk factors: 1. sociodemographic data (age, sex, ASA score, BMI, previous diseases). 2. disease-specific data (entity, duration of disease, previous treatment, clinical symptoms, preoperative laboratory parameters) 3. surgical method as well as postoperative complications (according to Clavien-Dindo as well as occurrence of pancreatic typical complications like fistulas) 4. histomorphological data (entity, acinar cell atrophy, fibsosis rate and inflammation percentage) 5. length of hospital stay as well as length of intensive care stay. | — |
Countries
Germany
Contacts
Public ContactUwe A. Wittel
Uniklinik Freiburg, Department für Allgemein- und Viszeralchirurgie
Outcome results
None listed