O14.1 O24.4 O26.9
Conditions
Interventions
Group 1: 1. Assessment of the predictive potential of the individual CVD risk after hypertensive pregnancy diseases (HPD
measured by serum lipids, hypertension, blood glucose levels, BMI and 10- and 30-year Framingham Risk Score) using innovative, sector-specific phenotypes of the retinal layers and characteristics of t
48-72h postpartum
6, 12 and 24 months postpartum)
2. Measurement of a reference group of healthy pregnant women (n= 100) as well as women with gestational diabetes (n= 100) in the second and third trimester and 48-72 h
Sponsors
Universitätsklinikum Leipzig, Abteilung Geburtsmedizin
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: pregnant, giving birth at the University Hospital Leipzig
Exclusion criteria
Exclusion criteria: fetal syndroms, maternal diseases like MS, ALS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Macular retinal layer thicknesses over ten layers in nine sectors, measured by SD-OCT at baseline, follow-up 1(FU1) to follow-up 4 (FU4) - Quantification of the vessel density of the three vascular plexi and measurement of the foveal avascular zone (FAZ) using OCT-A - Wall-to-lumen ratio of retinal vessels measured with AO at baseline time points, FU1-FU4 | — |
Secondary
| Measure | Time frame |
|---|---|
| - Angiogenic factors (sFlt-1/ PlGF) - Maternal Doppler of the Aa. uterine | — |
Countries
Germany
Contacts
Public ContactAnne Dathan-Stumpf
Universitätsklinikum Leipzig, Abteilung Geburtsmedizin
Outcome results
None listed