Non-bronchoscopic bronchoalveolar lavage (NB-BAL) in critically ill pediatric patients with severe respiratory failure (pARDS) after Hematopoietic stem-cell transplantation (HSCT) – a single-center experience

Non-bronchoscopic bronchoalveolar lavage (NB-BAL) in critically ill pediatric patients with severe respiratory failure (pARDS) after Hematopoietic stem-cell transplantation (HSCT) – a single-center experience - NB-BAL in pARDS after HSCT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032485

Enrollment

Registered

2025-08-06

Start date

2023-11-20

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric lung failure after hematopoietic stem cell transplantation.

Interventions

Group 1: A retrospective analysis including 12 intubated pediatric patients undergoing 17 NB-BALs in the setting of pARDS after HCST in our tertiary university hospital in the years 2017 – 2023 was pe

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: The treated patient is younger than 18 years. The treated patient has received a stem cell transplant. The patient is invasively ventilated due to pediatric respiratory failure. The patient received a NB-BAL.

Exclusion criteria

Exclusion criteria: Failure to meet inclusion criteria.

Design outcomes

Primary

Measure	Time frame
Detection of the effect of NB-BAL on ventilation and circulation measured by oxygenation index (OI) and vasoactive inotropic score (VIS).	—

Secondary

Measure	Time frame
Adverse event recording: Arrhythmias, pulmonary hemorrhage, pneumothorax. Recording of microbiological results	—

Countries

Germany

Contacts

Public ContactDaniel Matheisl

Universitätsklinikum Freiburg - Zentrum für Kinder- und Jugendmedizin - Klinik für Allgemeine Kinder- und Jugendmedizin

daniel.matheisl@uniklinik-freiburg.de+49 761-270-43840

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026