TaNeMo Study: The physiological effects of repetitive neuromuscular magnetic stimulation (rNMS) as a basis for therapy target-adapted neuromodulation [study period A]

TaNeMo Study: The physiological effects of repetitive neuromuscular magnetic stimulation (rNMS) as a basis for therapy target-adapted neuromodulation [study period A] - TaNeMo

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00032429

Enrollment

Registered

2023-09-05

Start date

2023-09-11

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G81.1

Interventions

Group 1: Healthy subjects will undergo a one time rNMS stimulation of the tibialis anterior muscle with different stimulation protocols. Prior, directly after and 30 minutes as well as 60 minutes afte

Eligibility

Sex/Gender

All

Age

20 Years to 30 Years

Inclusion criteria

Inclusion criteria: • Healthy subjects without any chronic disorder • All participants have to give written informed consent to participate in this study

Exclusion criteria

Exclusion criteria: • Orthopedic surgery of the lower extremity within the last 12 months • Contraindications for treatment with magnetic stimulation or MRI imaging: o Diagnosis of epilepsy o Ferromagnetic implant / biomedical device (e.g., cochlear implant, pacemaker, vagus nerve stimulator, ventriculo-peritoneal shunt) o Pregnancy o Claustrophobia

Design outcomes

Primary

Measure	Time frame
Are there effects on cortical excitability measured by nTMS (changes in MEP-amplitude) after T60 (60 minutes after rNMS stimulation) compared to T0 (baseline)?	—

Secondary

Measure	Time frame
1. Are there effects on cortical excitability measured by nTMS after T60 compared to T0 (baseline)? 2. Are there effects on cortical excitability measured by nTMS at T1 (directly after the rNMS stimulation) and T30 (30 minutes after the rNMS stimulation) compared to T0?	—

Countries

Germany

Contacts

Public ContactMichaela Bonfert

LMU Klinikum München, Dr. von Haunersches Kinderspital, Abteilung für Pädiatrische Neurologie, Entwicklungsneurologie, Sozialpädiatrie und LMU Zentrum für Entwicklung und komplex chronisch kranke Kinder - iSPZ Hauner

michaela.bonfert@med.lmu.de+49 1525 4923717

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026