Long-/post-COVID-19 syndrome
Conditions
Interventions
Group 1: The intervention group (TeR-INT) starts immediately (after randomization and stratification phase: 1 week after the medical and performance physiological initial examination: T0) with a syste
TAU). After 8 weeks and a midterm examination, the TeR-KG also receives a TeR and the TeR-INT receives a less close-meshed teletherapeutic care in an 8-week follow-up phase (instead of once a week, on
Sponsors
Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Voluntary participation Signature of the informed consent form Proven Covid-19 infection (PCR test and/or rapid antigen test provided by medical personnel). Diagnosed post-COVID syndrome
Exclusion criteria
Exclusion criteria: < 18 years No internet access and/or unable or unwilling to participate in the study Lack of capacity to give consent or doubts about capacity to give consent Participation in another rehabilitation program but this excludes individual medical services (such as psychotherapeutic therapy, GP visits). Red flags (Casser et al. 2016) and absolute contraindications to exercise and physical activity (American Thoracic Society 2003). Clinically significant 12-lead ECG abnormalities detected by the investigator and other symptoms (e.g., decreasing oxygen saturation) indicative of exercise intolerance Participation in another study Unable to perform a performance diagnostic test on a cycle ergometer Other unspecified reasons which, in the from the investigator's point of view speak against participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Both primary endpoints will be collected at all test time points (T0- Pre, T1- Post-INT, T2- Post Follow Up): - Maximum oxygen uptake [VO2peak (ml/min/kg)] - Regression quotient from minute ventilation and carbon dioxide production: VE/VCO2 slope [Full-Slope] | — |
Secondary
| Measure | Time frame |
|---|---|
| All secondary endpoints will be collected at all test time points (T0- Pre, T1- Post-INT, T2- Post Follow Up): - Submaximal and maximal exercise capacity (watts/kg) at ventilatory threshold 1 (VT1) and 2 (VT2) and at maximum oxygen uptake (VO2peak). - Respiratory economy: oxygen pulse, respiratory equivalent for carbon dioxide (ECO2) and end-tidal carbon dioxide content (PETCO2) at VT1 and VT2 and at end of exercise and Nijmegen Score (NQ Score) - The change in body shell temperature distribution in different body areas (ROI). - Inflammation [cytokines & cell-free genetic material (cfDNA)]. - Therapy adherence: number of training sessions performed (TE) / number of recommended TE - Patient Satisfaction - Post-exertional malaise (PEM questionnaire) - Somatization, depression and anxiety syndrome (Brief Symptom Inventory-18) - Severity of insomnia (Insomnia Severity Index) - Social support (Social Support Questionnaire Short Form) - Optimism and Pessimism (Optimism-Pessimism-2 Scale) - Self-efficacy (General Self-Efficacy Short Form Scale) | — |
Countries
Germany
Contacts
Public ContactPerikles Simon
Institut für Sportwissenschaft
Outcome results
None listed