Frailty gynecologic oncology
Conditions
Interventions
Group 1: Adult female patients (age = 60 years and/or BMI (Body Mass Index) = 35kg/m² and/or subjectively frail) with a confirmed diagnosis of a gynecological tumor, regardless of the clinical stage,
Sponsors
Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Abteilung Klinik und Poliklinik für Geburtshilfe und Frauengesundheit
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Adult female patients (age = 60 years and/or BMI (Body Mass Index) = 35kg/m² and/or subjectively frail) with a confirmed diagnosis of a gynecological tumor, regardless of the clinical stage, treatment type, and treatment line, who require stage-appropriate surgical therapy.
Exclusion criteria
Exclusion criteria: - Lack of histological confirmation - Benign pathology - Missing informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation of frailty status with postoperative complications in patients with gynecological tumors | — |
Secondary
| Measure | Time frame |
|---|---|
| - progression-free survival (PFS), disease specific survival (DSS) and overall survival (OS) and correlation with the preoperative screening tools - length of hosptial stay and readmission rate - Influence of the comprehensive geriatric assessment on the outcome of the frail cohort - collection of preoperative risk factors - correlation of screening tests, laboratory results and clinical parameters with PFS, DSS and OS - screening of potential biomarkers for frailty in serum and saliva | — |
Countries
Germany
Contacts
Public ContactValerie Linz
Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Abteilung Klinik und Poliklinik für Geburtshilfe und Frauengesundheit
Outcome results
None listed