Evaluation of the non-invasive PADFEX method for detecting respiratory pathogens in lung transplant recipients

Evaluation of the non-invasive PADFEX method for detecting respiratory pathogens in lung transplant recipients - PADFEX-LTx

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032359

Enrollment

Registered

2023-07-27

Start date

2022-03-25

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J22

Interventions

Group 1: Multiplex PCR ofs Spotum, swabs , BAL (bronchoalveolar lavage)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Post lung transplantation with indication for bronchoalveolar lavage (BAL) due to suspected respiratory infection, defined as meeting at least 2 of the following criteria within the last 7 days: acute feeling of illness, new shadowing on X-ray, new hypoxemia, temperature higher than 38 degrees Celsius, CRP greater than 30 mg/L, or procalcitonin less than 0.5 micrograms per liter, or known respiratory tract colonization.

Exclusion criteria

Exclusion criteria: no informed consent

Design outcomes

Primary

Measure	Time frame
Sensitivity and specificity compared to nasal swabs, sputum, and BAL. mit multiplex PCR	—

Secondary

Measure	Time frame
Sensitivity and specificity compared to nasal swabs, sputum, and BAL. of multiplex PCR in comparison to standard work-up	—

Contacts

Public ContactJENS GOTTLIEB

MHH

gottlieb.jens@mh-hannover.de05115324681

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026