Evaluation of gingival perfusion when using platelet-rich-fibrin (PRF) for tooth extractions - A prospective randomized study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032344

Enrollment

Registered

2023-10-11

Start date

2023-07-25

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K08.88

Interventions

Group 1: Pat. with a single tooth extraction where no PRF is inserted Group 2: Patient with a single tooth extraction where a PRF cone is inserted

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: The exclusion criteria are inoperable patients, patients with an acute abscess before tooth extraction, patients with blood clotting problems, minors, pregnant women and patients taking antibiotics or medication that affect blood circulation or the physiological state of the intraoral mucous membranes.

Exclusion criteria

Exclusion criteria: The exclusion criteria are inoperable patients, patients with an acute abscess before tooth extraction, patients with blood clotting problems, minors, pregnant women, and patients taking antibiotics or medication that affect blood circulation or the physiological state of the intraoral mucous membranes.

Design outcomes

Primary

Measure	Time frame
Is the perfusion in patients who have PRF inserted after tooth extraction different from patients who do not have PRF inserted?	—

Secondary

Measure	Time frame
Can PRF reduce postoperative pain after tooth extraction?	—

Countries

Germany

Contacts

Public ContactMarie Sophie Katz

Klinik für MKG-Chirurgie der Uniklinik RWTH Aachen

mkatz@ukaachen.de+49 241 8088231

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026