Failure to thrive
Conditions
Interventions
Group 1: Human milk is the recommended diet for preterm infants. Due to the rapid growth and energy requirements of preterm infants, human milk alone is not sufficient to support their growth at the s
Sponsors
Klinikum der LMU München, Neonatologie der Kinderklinik
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Preterms < 28 weeks GA and Preterms < 1250g who receive standard fortified breast milk are included
Exclusion criteria
Exclusion criteria: - Infants with known congenital anomalies or metabolic disorders - Infants that have already obtained fortified breastmilk for more than 5 days when transferred to NICUs of the LMU Hospital - Infants of parents who are not planning or cannot provide human milk - Infants who have or develop severe complications, e.g.NEC, so that enteral feeding and/or fortification is interrupted (on 3 or more days less than 115/kcal/kg/day enteral energy intake) which would significantly affect growth (Study aim 2) - Infants who are also fed with formula once the measurement period started due to insufficient amount of mother’s own milk (more than 10% of the enteral intake on three days or more during the measurement period).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Macronutrient content (carbohydrates, protein, fat) in the administered breast milk or donor milk. | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare the growth of preterm infants whose macronutrient intake through standard fortification meets the ESPGHAN recommendations to those preterm infants whose nutritional levels fall outside the recommendations due to human milk composition being below reference values. | — |
Countries
Germany
Contacts
Public ContactCarmen Jakubowicz
Klinikum der LMU München, Neonatologie der Kinderklinik
Outcome results
None listed