Immediate implant placement versus alveolar ridge preservation with delayed implant placement: a randomized controlled clinical trial on patient-reported outcome measures (IIP vs ARP)

Immediate implant placement versus alveolar ridge preservation with delayed implant placement: a randomized controlled clinical trial on patient-reported outcome measures (IIP vs ARP) - IIP vs ARP

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00032281

Enrollment

Registered

2023-08-10

Start date

2024-01-09

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K00-K14

Interventions

Group 1: Immediate implant placement (IIP) Group 2: Alveolar ridge preservation (ARP) followed by Implant placement

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Presence of a failing tooth in the anterior region • Planned implant site with at least one neighboring tooth present • Periodontally healthy patients (periodontal probing depths ? 4 mm) (full mouth) • Good oral hygiene (full mouth plaque index <25%; (O'Leary et al., 1972) • Adequate control of inflammation (full mouth bleeding on probing <25%; (Ainamo & Bay, 1975) • Capability to comply with the study procedures • Informed consent as documented by signature

Exclusion criteria

Exclusion criteria: • Pregnant or lactating women • Known or suspected non-compliance, drug or alcohol abuse • Smokers (>10 cigarettes/day) • Currently taking drugs that influence bone metabolism • Systemic or local conditions presenting a contraindication to implant treatment • Use of bisphosphonates in the last 5 years • History of radiotherapy or chemotherapy for malignancy in the past 5 years

Design outcomes

Primary

Measure	Time frame
The primary outcome of the study will be the midfacial mucosal recession between pre-extraction and crown delivery ( 2 weeks after crown delivery).	—

Secondary

Measure	Time frame
-Overall patient satisfaction at several timepoints -OHIP-14 at several time points - Pain evaluation after each intervention (extraction and implant placement) - Overall dentist satisfaction at several time points - Horizontal thickness (in mm) of the regenerated bone at the buccal aspect of the implant at several time points - Clinical parameters (PD, PCR, mBSI, BOP, KM, crown height) of the study site and of the adjacent teeth at screening and at the different later time-points	—

Measure

Time frame

-Overall patient satisfaction at several timepoints -OHIP-14 at several time points - Pain evaluation after each intervention (extraction and implant placement) - Overall dentist satisfaction at several time points - Horizontal thickness (in mm) of the regenerated bone at the buccal aspect of the implant at several time points - Clinical parameters (PD, PCR, mBSI, BOP, KM, crown height) of the study site and of the adjacent teeth at screening and at the different later time-points

—

Countries

Serbia, Switzerland

Contacts

Public ContactDaniel Thoma

Zentrum für Zahnmedizin, Universität Zürich

daniel.thoma@zzm.uzh.ch+41 44 634 04 04

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026