Influence of zinc substitution on the immune function of probands with vegetarian and vegan lifestyle

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00032264

Enrollment

100

Registered

2025-03-24

Start date

2023-08-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reduced zinc intake, which is not strictly fullfilling the ICD 10 code E60 for zinc deficiency.

Interventions

Group 1: Vegans and Vegetarians Zinc supplementation: 10mg zinc per day for 14 days

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Vegetarian or vegan for at least 3 months

Exclusion criteria

Exclusion criteria: Acute Infection Intake of immune suppressive drugs Pregnancy Younger than 18 years Drug or alcohol abuse BMI over 29

Design outcomes

Primary

Measure	Time frame
Immune Response Leukocyte subpopulations and functions are measured before and after zinc supplementation. Leukocyten subpopulations are measured by flow cytometry and Leukocyten functions are measured by cytokine production and functional tests (cytotoxicity assay, proliferation, phagocytosis assay, burst assay etc.).	—

Secondary

Measure	Time frame
Interleukin-2 Production The measurements by ELISA are performed before and after zinc supplementation.	—

Countries

Germany

Contacts

Public ContactLothar Rink

Institut für Immunologie

LRink@UKAachen.de+49 241 8080208

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026