Long-term outcome of critical illness and post-intensive care syndrome

Long-term outcome of critical illness and post-intensive care syndrome - LOCPICS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032236

Enrollment

250

Registered

2023-08-03

Start date

2024-06-12

Completion date

Unknown

Last updated

2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-Intensive Care Syndrome A41.8 F06.3 F32.9 F06.7 G62.8 G72.8

Interventions

Group 1: Patient:inside after intensive medical treatment

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age = 18 years Intensive care treatment > 72h

Exclusion criteria

Exclusion criteria: non

Design outcomes

Primary

Measure	Time frame
The primary endpoint is the diagnosis of PICS by at least one abnormality in one of the domains	—

Secondary

Measure	Time frame
- Subdomains of the PICS or number of PICS domains affected. - Physical function (including Barthel index, timed Up-and-Go, Short Physical Performance Battery Test (SPPB), hand strength, bioimpedance analysis). - Quality of life (e.g. European Quality of Life 5 Dimensions 5 Level (EQ5D-5L)) - Cognitive function (e.g. MiniCog, animal naming test, Trail Making Test A+B) - Disability (WHO Disability Assessment Schedule 2.0 (WHODAS 2.0)) - Mental health (Patient Health Questionnaire-4 (PHQ-4) and Patient Health Questionnaire-8 (PHQ-8) Generalized Anxiety Disorder Scale-7 (GAD-7), Impact of Event Scale - Revised (IES-R)) - Swallowing disorders - Health care needs (duration of ventilation, intensive care and hospital stay, rehabilitation duration, nursing care needs, medication needs) - Nutritional status (including MNA short/long, NRS 2002, MUST, SGA, PG-SGA, weight change, abdominal circumference, skin thickness) - If other tests are added to survey for PICS, they will also be included - Exploratory evaluation of routine clinical data will be performed	—

Measure

Time frame

- Subdomains of the PICS or number of PICS domains affected. - Physical function (including Barthel index, timed Up-and-Go, Short Physical Performance Battery Test (SPPB), hand strength, bioimpedance analysis). - Quality of life (e.g. European Quality of Life 5 Dimensions 5 Level (EQ5D-5L)) - Cognitive function (e.g. MiniCog, animal naming test, Trail Making Test A+B) - Disability (WHO Disability Assessment Schedule 2.0 (WHODAS 2.0)) - Mental health (Patient Health Questionnaire-4 (PHQ-4) and Patient Health Questionnaire-8 (PHQ-8) Generalized Anxiety Disorder Scale-7 (GAD-7), Impact of Event Scale - Revised (IES-R)) - Swallowing disorders - Health care needs (duration of ventilation, intensive care and hospital stay, rehabilitation duration, nursing care needs, medication needs) - Nutritional status (including MNA short/long, NRS 2002, MUST, SGA, PG-SGA, weight change, abdominal circumference, skin thickness) - If other tests are added to survey for PICS, they will also be included - Exploratory evaluation of routine clinical data will be performed

—

Countries

Germany

Contacts

Public ContactClaudia Spies

Klinik für Anästhesiologie und Intensivmedizin CCM/CVK

claudia.spies@charite.de+4930450551002

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026